compound introduction
Bayer-18 是TYK2的抑制剂。Bayer-18 抑制间变性大细胞淋巴瘤细胞 K299，SR786，Mac1 和 Mac2a 活力，IC50为 2-3 µM，并在 K299 和 SR786 细胞中诱导凋亡 (apoptosis)。
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1-(Tert-butyl)-3-(3-((5-fluoro-4-((1-hydroxy-2-methylpropan-2-yl)amino)pyrimidin-2-yl)amino)phenyl)urea
CAS number：1251752-12-1 molecular formula：C19H27FN6O2
overview
Specs
| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 1251752-12-1 | molecular formula | C19H27FN6O2 |
| molecular weight | 390.46 g/mol | Exact mass | - |
| PSA | 111.000 Ų | logp | 2.400 |
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