compound introduction
INI-43 是Kpnβ1的抑制剂，干扰 Kpnβ1 和已知的 Kpnβ1 cargo 蛋白、NFAT、NFκB、AP-1和 NFY 的核定位。INI-43 能抑制癌细胞的增殖，在癌细胞中引起 G2-M 细胞周期阻滞，并诱导细胞内在凋亡 (apoptosis) 途径。
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2-Amino-3-(1H-benzimidazol-2-yl)-N,N-dimethyl-1H-pyrrolo(2,3-b)quinoxaline-1-propanamine
CAS number：881046-01-1 molecular formula：C22H23N7
overview
Specs
| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 881046-01-1 | molecular formula | C22H23N7 |
| molecular weight | 385.46 g/mol | Exact mass | ≥99% |
| PSA | 88.700 Ų | logp | 2.900 |
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