Broussochalcone A 是一种抗氧化剂和黄嘌呤氧化酶抑制剂 (IC50=2.21 μM),具有自由基清除活性。Broussochalcone A 抑制铁诱导的脂质过氧化,抑制脂多糖 (LPS) 激活的巨噬细胞中的一氧化氮 (NO) 的合成。Broussochalcone A 还通过提高 ROS 水平和激活 FOXO3 信号通路诱导人肾癌细胞凋亡 (Apoptosis)。
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Broussochalcone A
CAS number:99217-68-2 molecular formula:C20H20O5
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Specs
| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 99217-68-2 | molecular formula | C20H20O5 |
| molecular weight | 340.400 g/mol | Exact mass | - |
| PSA | 98.000 Ų | logp | 4.700 |
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