compound introduction
CAY10789 (化合物 6) 是一种有效的CysLT1R拮抗剂 (IC50=2.80 μM) 和GPBAR1激动剂 (EC50=3 μM)。CAY10789 显著降低 U937 细胞对 HAEC 的粘附，降低 TNF-α 的表达。CAY10789 具有良好的代谢稳定性和良好的药代动力学。 CAY10789 可用于结肠炎、代谢综合征等 GPBAR1/CysLT1R 相关疾病的研究。
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Benzenemethanol, 3-(2-quinolinylmethoxy)-
CAS number：123226-28-8 molecular formula：C17H15NO2
overview
Specs
| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 123226-28-8 | molecular formula | C17H15NO2 |
| molecular weight | 265.31 g/mol | Exact mass | ≥99% |
| PSA | 42.400 Ų | logp | 2.800 |
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