compound introduction
TR-14035 是一种α4β7/α4β1 整合素 (α4β7/α4β1 integrin) 双重抑制剂，对 α4β7 和 α4β1 作用的 IC50 值分别为 7 nM 和 87 nM。TR-14035 可用于炎症和自体免疫疾病的研究。
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TR 14035
CAS number：232271-19-1 molecular formula：C24H21Cl2NO5
overview
Specs
| Chinese alias | (αS)-α-[((2,6-二氯苯甲酰基)氨基] -2',6'-二甲氧基[1,1'-联苯] -4-丙酸 | ||
| English alias | (2S)-2-((2,6-DICHLOROBENZOYL)AMINO)-3-(4-(2,6-DIMETHOXYPHENYL)PHENYL)PROPANOIC ACID | (S)-2-(2,6-Dichlorobenzamido)-3-(2',6'-dimethoxy-[1,1'-biphenyl]-4-yl)propanoic acid | N-(2,6-Dichlorobenzoyl)-4-(2',6'-bismethoxyphenyl)phenylalanine | (1,1'-Biphenyl)- | ||
| CAS number | 232271-19-1 | molecular formula | C24H21Cl2NO5 |
| molecular weight | 474.33 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 84.900 Ų | logp | 5.600 |
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