CAS number：116686-15-8 molecular formula：C15H13F2NO4S
product description： A cell-permeable and orally available sulfonanilide that acts as a COX-2-selective non-steroidal anti-inflammatory drug (NSAID). Shown to exhibit 500-fold greater potency in inhibiting the LPS-induced (IC50 = 316 nM in human mononuclear cells) than the non-induced/constitutive (IC50 = 160 µM in human platelets) TxB2 production in vitro and effectively alleviate warm ischemia-reperfusion injury in the canine liver and rat lung in vivo.
| Chinese alias | N-[4-乙酰基-2-(2,4-二氟苯氧基)苯基]甲磺酰胺 | ||
| English alias | DTXSID90151474 | EX-A545 | AC-35975 | AKOS024457289 | N-(4-Acetyl-2-(2,4-difluorophenoxy)phenyl)methanesulfonamide | FK 3311 | A13332 | Methanesulfonamide, N-[4-acetyl-2-(2,4-difluorophenoxy)phenyl]- | COX-2 Inhibitor V, FK3311 - CAS 116686-15-8 | FK3311 | ||
| CAS number | 116686-15-8 | molecular formula | C15H13F2NO4S |
| molecular weight | 341.33 g/mol | Exact mass | 10mM in DMSO |
| PSA | 80.900 Ų | logp | 2.300 |
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