NOS-IN-1 (2-Imino-4-methylpiperidine acetate) 是有效的一氧化氮合酶 (NOS) 的抑制剂。NOS-IN-1抑制人 iNOS (hiNOS),hnNOS 和 heNOS 的 IC50 分别为 0.1 μM,0.2 μM 和1.1 μM。 2-Imino-4-methylpiperidine acetate is a potent, general NOS inhibitor. 2-Imino-4-methylpiperidine exhibits IC|50|values of 0.1, 1.1, and 0.2 μM for inhibition of human NOS2 (iNOS), NOS3 (eNOS), and NOS1 (nNOS), respectively, at an arginine concentration of 30 μM.
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2-Imino-4-methylpiperidine acetate
CAS number:165383-72-2 molecular formula:C8H16N2O2
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| Chinese alias | - | ||
| English alias | 4-methyl-2,3,4,5-tetrahydropyridin-6-amine | NOS-IN-1 | ||
| CAS number | 165383-72-2 | molecular formula | C8H16N2O2 |
| molecular weight | 178.22 g/mol | Exact mass | ≥98% |
| PSA | 75.700 Ų | logp | - |
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