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YKL 06-061

CAS number:2172617-15-9    molecular formula:C30H37N7O2

overview

compound introduction

Information YKL 06-061 YKL 06-061 is a potent and selective salt-inducible kinase (SIK) inhibitor with IC50 of 6.56 nM, 1.77 nM and 20.5 nM for SIK1, SIK2 and SIK3, respectively. Targets SIK2 (Cell-free assay); SIK1 (Cell-free assay); SIK3 (Cell-free assay) 1.77 nM; 6.56 nM; 20.5 nM

Specs

Chinese alias-
English aliasPyrimido[4,​5-​d]​pyrimidin-​2(1H)​-​one,1-​cyclobutyl-​3-​(2,​6-​dimethylphenyl)​-​3,​4-​dihydro-​7-​[[2-​methoxy-​4-​(4-​methyl-​1-​piperazinyl)​phenyl]​amino]​-
CAS number2172617-15-9molecular formulaC30H37N7O2
molecular weight527.66 g/molExact mass10mM in DMSO
PSA77.100 Ųlogp5.541

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