CAS number：256373-96-3 molecular formula：C20H23N2NaO5S
MCC950 sodium (CP-456773 sodium; CRID3 sodium salt) 是一种有效，选择性的 NLRP3 抑制剂，在BMDMs 和 HMDMs中的 IC50 分别为 7.5 nM 和 8.1 nM。 application： CP-456773 sodium salt has been used : In in vivo experiments to study the neuroprotective action of ketogenic diet. To study the effect of inhibition of NLRP3 (nod-like receptor protein 3) inflammasome activity on tumor progression in mouse models. To study the cholesterol crystal-mediated IL-1b (interleukin-1b) response in placental explants.
| Chinese alias | MCC950钠盐 | CP-456773钠盐 | [(1,2,3,5,6,7-六氢-s-引达省-4-基)氨基甲酰基][[4-(2-羟基丙烷-2-基)呋喃-2-基]磺酰基]酰胺钠 | CP-456773 钠盐 | N-[[(1,2,3,5,6,7-六氢-s-吲达辛-4-基)氨基]羰基] -4-(1-羟基-1-甲基乙基)-2-呋喃磺酰胺 钠盐 | MCC950, 细胞因子释放抑制药物 3, CRID3 | ||
| English alias | KBio1_000672 | sodium 1,2,3,5,6,7-hexahydro-s-indacen-4-ylcarbamoyl-[[4-(1-hydroxy-1-methyl-ethyl)-2-furyl]sulfonyl]azanide | MCC950 sodium salt | AKOS025147369 | EN300-214108 | s7809 | MCC950 (CP-456773) sodium | ethyl 1,4-dihydro-7-methoxy-4-oxoquinolin | ||
| CAS number | 256373-96-3 | molecular formula | C20H23N2NaO5S |
| molecular weight | 426.46 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 106.000 Ų | logp | - |
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