CAS number：1996629-79-8 molecular formula：C24H21F3N2O4S
Information TBOPP TBOPP is a selective inhibitor of dedicator of cytokinesis (DOCK1, Dock180) that inhibits DOCK1-mediated Rac activation with IC50 of 8.4 μM. TBOPP binds to the DOCK1 DHR-2 domain with Kd of 7.1 μM. TBOPP exhibits anti-tumor activity. Targets DOCK1 DHR-2 domain (Cell-free assay); DOCK1-mediated Rac activation (Cell-free assay) 7.1 μM(Kd); 8.4 μM
| Chinese alias | - | ||
| English alias | 2(1H)-Pyridinone,1-[2-oxo-2-[3'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]ethyl]-5-(1-pyrrolidinylsulfonyl)- | ||
| CAS number | 1996629-79-8 | molecular formula | C24H21F3N2O4S |
| molecular weight | 490.49 g/mol | Exact mass | ≥99% |
| PSA | 83.100 Ų | logp | 2.881 |
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