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JH-X-119-01

CAS number:2227368-54-7    molecular formula:C25H20N6O3

overview

compound introduction

JH-X-119-01 是一种有效的选择性白介素 1 受体相关激酶 1 (IRAK1) 抑制剂。JH-X-119-01 可改善 LPS 诱导的小鼠败血症。JH-X-119-01 抑制 IRAK1,IC50 为 9 nM,而在浓度高达 10 μM 时对 IRAK4 也没有抑制作用。

Specs

Chinese alias-
English alias-
CAS number2227368-54-7molecular formulaC25H20N6O3
molecular weight452.46 g/molExact mass≥97%
PSA129.000 Ųlogp2.600

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