JH-X-119-01 是一种有效的选择性白介素 1 受体相关激酶 1 (IRAK1) 抑制剂。JH-X-119-01 可改善 LPS 诱导的小鼠败血症。JH-X-119-01 抑制 IRAK1,IC50 为 9 nM,而在浓度高达 10 μM 时对 IRAK4 也没有抑制作用。
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JH-X-119-01
CAS number:2227368-54-7 molecular formula:C25H20N6O3
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 2227368-54-7 | molecular formula | C25H20N6O3 |
| molecular weight | 452.46 g/mol | Exact mass | ≥97% |
| PSA | 129.000 Ų | logp | 2.600 |
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