CAS number：1229603-37-5 molecular formula：C20H29ClFN5O2\n
AZD2423 is a potent, selective, orally bioavailable, and non-competitive CCR2 chemokine receptor negative allosteric modulator. AZD2423 has an IC 50 of 1.2 nM for CCR2 Ca 2+ flux In Vitro AZD2423 inhibits MCP-1 induced calcium mobilization and chemotaxis of THP-1 cell line with an IC 50 of 4 nM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:CCR2
| Chinese alias | - | ||
| English alias | 1W47471992 | AKOS040741194 | UNII-1W47471992 | 4-[(2R)-4-tert-butylpiperazine-2-carbonyl]-N-(4-chloro-3-fluorophenyl)piperazine-1-carboxamide | SCHEMBL2492309 | 1229603-37-5 | SRWQVWAIVQXPJY-QGZVFWFLSA-N | AZD2423 | AZD-2423 | HY-135891 | AZD 2423 [WHO-DD | ||
| CAS number | 1229603-37-5 | molecular formula | C20H29ClFN5O2\n |
| molecular weight | 425.93 g/mol | Exact mass | ≥98% |
| PSA | 67.900 Ų | logp | 1.500 |
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