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CA-170

CAS number:1673534-76-3    molecular formula:

overview

compound introduction

CA-170 is an orally delivered dual inhibitor of VISTA and PD-L1 . CA-170 exhibits potent rescue of proliferation and effector functions of T cells inhibited by PD-L1/L2 and VISTA with selectivity over other immune checkpoint proteins as well as a broad panel of receptors and enzymes. Form:Solid IC50& Target:PD-1 In Vitro:CA-170 exhibits potent functional activity in rescuing T-cell proliferation and effector functions, while showing selectivity against other immune checkpoint proteins as well as in a broad panel of receptors and enzymes. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Specs

Chinese alias-
English aliasAurigene 1 | N-{[(1S)-3-Amino-1-{3-[(1R)-1-amino-2-hydroxyethyl]-1,2,4-oxadiazol-5-yl}-3-oxopropyl]carbamoyl}-L-threonine | CA-170 | EX-A1918 | (((S)-3-amino-1-(3-((R)-1-amino-2-hydroxyethyl)-1,2,4-oxadiazol-5-yl)-3-oxopropyl)carbamoyl)-L-threonine | NSC7
CAS number1673534-76-3molecular formula
molecular weight360.320 g/molExact mass≥99%
PSA227.000 Ųlogp-6.700

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