CA-170 is an orally delivered dual inhibitor of VISTA and PD-L1 . CA-170 exhibits potent rescue of proliferation and effector functions of T cells inhibited by PD-L1/L2 and VISTA with selectivity over other immune checkpoint proteins as well as a broad panel of receptors and enzymes. Form:Solid IC50& Target:PD-1 In Vitro:CA-170 exhibits potent functional activity in rescuing T-cell proliferation and effector functions, while showing selectivity against other immune checkpoint proteins as well as in a broad panel of receptors and enzymes. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
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CA-170
CAS number:1673534-76-3 molecular formula:
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| Chinese alias | - | ||
| English alias | Aurigene 1 | N-{[(1S)-3-Amino-1-{3-[(1R)-1-amino-2-hydroxyethyl]-1,2,4-oxadiazol-5-yl}-3-oxopropyl]carbamoyl}-L-threonine | CA-170 | EX-A1918 | (((S)-3-amino-1-(3-((R)-1-amino-2-hydroxyethyl)-1,2,4-oxadiazol-5-yl)-3-oxopropyl)carbamoyl)-L-threonine | NSC7 | ||
| CAS number | 1673534-76-3 | molecular formula | |
| molecular weight | 360.320 g/mol | Exact mass | ≥99% |
| PSA | 227.000 Ų | logp | -6.700 |
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