CAS number：51589-67-4 molecular formula：C21H20O4
4-Methoxylonchocarpin 是一种口服有效的抗炎剂。4-Methoxylonchocarpin 抑制 LPS 与 Toll 样受体 4 (TLR4) 的结合来抑制NF-κB活化以及肿瘤坏死因子 (TNF) 和白细胞介素IL-6的表达。4-Methoxylonchocarpin 还抑制 TGF-beta 激活激酶 1 的磷酸化和 2,4,6-三硝基苯磺酸 (TNBS) 诱导的 IL-1β、IL-17A 和 TNF 表达。4-Methoxylonchocarpin 能改善 TNBS 诱导的结肠炎小鼠模型。
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| CAS number | 51589-67-4 | molecular formula | C21H20O4 |
| molecular weight | 336.400 g/mol | Exact mass | ≥98% |
| PSA | 55.800 Ų | logp | 4.800 |
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