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Fmoc-Ala-Thr(psi(Me,Me))-OH

CAS number:252554-79-3    molecular formula:C25H28N2O6

overview

compound introduction

Fmoc-Ala-Thr(psi(Me,Me))-OH是Fmoc保护的丙氨酸衍生物,可能对蛋白质组学研究和固相肽合成技术有用。丙氨酸是最简单的氨基酸之一-甲基为侧链。当掺入多肽链时,该小侧链赋予高度的灵活性(仅次于甘氨酸)。通常用诸如吡啶之类的碱除去Fmoc基团-这是酸性labile Boc基团的正交脱保护策略。 Fmoc-Ala-Thr(psi(Me,Me))-OH is an Fmoc protected alanine derivative that is potentially useful for proteomics studies and solid phase peptide synthesis techniques. Alanine is one of the simplest amino acids - a methyl group as the side chain. This small side chain confers a high degree of flexibility (second only to glycine) when incorporated into a polypeptide chain. The Fmoc group is typically removed with a base such as pyridine - an orthogonal de-protection strategy to the acid labilie Boc group.

Specs

Chinese alias-
English aliasFmoc-Ala-Thr[y(Me,Me)Pro]-OH | (4S,5R)-3-(Fmoc-Ala)-2,2,5-trimethyl-oxazolidine-4-carboxylic acid
CAS number252554-79-3molecular formulaC25H28N2O6
molecular weight452.51 g/molExact mass≥98%
PSA105.000 Ųlogp3.400

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MSDS

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252554-79-3 | Fmoc-Ala-Thr(psiMe,Mepro)-OH Novabio-chem®.pdf