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Fmoc-beta-chloro-L-alanine

CAS number:212651-52-0    molecular formula:C18H16ClNO4

overview

compound introduction

Fmoc-β-氯-L-丙氨酸是Fmoc保护的丙氨酸衍生物,可能对蛋白质组学研究和固相肽合成技术有用。丙氨酸是最简单的氨基酸之一-甲基为侧链。当掺入多肽链时,该小侧链赋予高度的灵活性(仅次于甘氨酸)。通常用诸如吡啶之类的碱除去Fmoc基团-这是酸性labile Boc基团的正交脱保护策略。 Fmoc-beta-chloro-L-alanine is an Fmoc protected alanine derivative that is potentially useful for proteomics studies and solid phase peptide synthesis techniques. Alanine is one of the simplest amino acids - a methyl group as the side chain. This small side chain confers a high degree of flexibility (second only to glycine) when incorporated into a polypeptide chain. The Fmoc group is typically removed with a base such as pyridine - an orthogonal de-protection strategy to the acid labilie Boc group.

Specs

Chinese alias-
English aliasDTXSID101203107 | Fmoc-beta-chloro-L-alanine | Fmoc-3-Chloro-L-alanine | J-013962 | AKOS015837250 | E70530 | Fmoc-beta-Chloro-L-Ala-OH | (2R)-3-chloro-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propanoic acid | MFCD00270534 | (R)-2-((((9H-Fluoren-9-yl)met
CAS number212651-52-0molecular formulaC18H16ClNO4
molecular weight345.79 g/molExact mass≥98%
PSA75.600 Ųlogp3.300

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