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Fmoc-Asp(OEpe)-OH

CAS number:unknown    molecular formula:

overview

compound introduction

Description An excellent derivative for minimizing aspartimide formation during Fmoc SPPS of Asp-containing peptides. The bulky OEpe protecting group offers considerably more protection against the formation of aspartimide-related by-products than the commonly used OtBu and OMpe group. The combination of Asp(OEpe) and the use of 1 M Oxyma Pure in DMF for Fmoc removal results in minimal aspartimde formation. Description An excellent derivative for minimizing aspartimide formation during Fmoc SPPS of Asp-containing peptides. The bulky OEpe protecting group offers considerably more protection against the formation of aspartimide-related by-products than the commonly used OtBu and OMpe group. The combination of Asp(OEpe) and the use of 1 M Oxyma Pure in DMF for Fmoc removal results in minimal aspartimde formation.

Specs

Chinese alias-
English aliasN-α-Fmoc-(O-3-ethyl-pent-3-yl)aspartic acid, Fmoc-Asp(OEpe)-OH
CAS numberunknownmolecular formula
molecular weight-Exact massReagent Grade
PSA-logp-

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