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1400W (iNOS inhibitor)

CAS number:unknown    molecular formula:

overview

compound introduction

1400W,即N-3-(Aminomethyl)benzyl]acetamidine,Dihydrochloride,是iNOS(induciblenitricoxide synthase)高度选择性抑制剂。对于iNOS,Kd=7nM。对于人iNOS的抑制能力比对人eNOS和nNOS的抑制能力分别高5000倍和200倍。1400W为白色固体,分子量250.2,分子式为C10H15N3·2HCl,纯度大于95%。溶解于水或甲醇。 注意事项 : 如果配制成水溶液,分装后-20℃保存,三个月有效。 本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。为了您的安全和健康,请穿实验服并戴一次性手套操作。 使用说明 : 1400W的工作浓度通常为100μM。其最佳工作浓度需根据具体的实验,自行摸索。 Precautions : After this product is reconstituted into an aqueous solution, aliquot and store at -20℃ for up to 3 months.This product is for R&D only. Not for drug, household, or other uses.For your safety and health, please wear a lab coat and disposable gloves during the operation. Instructions for Use : The working concentration of 1400W is usually 100µM, but the optimal working concentration should be determined for each experiment.

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