Leukotriene B5 (LTB5) 是一种具有多种生物活性的白三烯。它是二十碳五烯酸通过 5-脂氧合酶 (5-LO) 途径形成的代谢物。LTB5 以浓度依赖性方式增加牛蛙肺条体外收缩。在体内,LTB5 (100 nM) 可减少注射 Tm1 鼠黑色素瘤细胞的小鼠的肿瘤体积。LTB5 还诱导多形核白细胞 (PMNL) 的趋化运动和溶酶体酶释放,强度比 LTB4 低 20 至 30 倍,诱导血小板聚集的强度低 8 倍。
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Leukotriene B5
CAS number:80445-66-5 molecular formula:
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 80445-66-5 | molecular formula | |
| molecular weight | 334.400 g/mol | Exact mass | - |
| PSA | 77.800 Ų | logp | 3.400 |
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