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Kinase Tracer 222, 50 µM

CAS number:unknown    molecular formula:

overview

compound introduction

Product introduction: Kinase Tracer 222 is an Alexa Fluor™ 647 dye-labeled, ATP-competitive kinase inhibitor scaffold for use in the LanthaScreen™ Eu Kinase Binding Assay. The LanthaScreen™ Eu Kinase Binding Assay • Is easily optimized • Measures inhibitor binding • Performs simple off-rate measurements Easily Screen for Kinase Binding The LanthaScreen™ Eu Kinase Binding Assay is a TR-FRET assay that lets you measure inhibitor binding to non-activated kinases, perform simple off-rate measurements, and makes simple the study of type III (allosteric) inhibitors. The LanthaScreen™ Eu Kinase Binding Assay is easy to optimize and run. The assay uses a simple mix-and-read format with a single one hour incubation and no development steps. Binding of an Alexa Fluor™ conjugate or “tracer” to a tagged kinase is detected by addition of a europium-labeled anti-tag antibody, in this case anti-GST. Simultaneous binding of the tracer and antibody to the kinase results in a high degree of fluorescence resonance energy transfer (TR-FRET), while displacement of the tracer with a kinase inhibitor results in a loss of TR-FRET. For Research Use Only. Not intended for any animal or human therapeutic or diagnostic use. • For Use With(Equipment): Microplate Reader • Color: Red

Specs

Chinese alias激酶示踪剂 222,50 µM
English alias-
CAS numberunknownmolecular formula
molecular weight-Exact mass-
PSA-logp-

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