DDO-5936 is a potent and specific Hsp90-Cdc37 PPI inhibitor. DDO-5936 can be used for the research of colorectal cancer In Vitro DDO-5936 is a Hsp90-Cdc37 PPI inhibitor with potency and specificity through binding to a critical site on Hsp90 involving Glu47. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo DDO-5936 (0~80 mg/kg; p.o.) shows effect at the high dose group . DDO-5936 is well tolerated for the absence of serious weight loss. DDO-5936 high dose groups show that tumor cells in the xenografts decreased significantly. DDO-5936 shows limited oral efficiency . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Mice Dosage: 0~80 mg/kg Administration: P.o. Result: Showed a moderate effect at the high dose group. IC50& Target:Hsp90-Cdc37 PPI
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DDO-5936
CAS number：2355377-13-6(DMSO) molecular formula：C25H29N5O4S
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 2355377-13-6(DMSO) | molecular formula | C25H29N5O4S |
| molecular weight | 495.6 g/mol | Exact mass | 10mM in DMSO |
| PSA | - | logp | - |
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