compound introduction
(S)-PI3Kα-IN-4 is a potent inhibitor of PI3Kα , with an IC 50 of 2.3 nM. (S)-PI3Kα-IN-4 shows 38.3-, 4.25-, and 4.93-fold selectivity for PI3Kα over PI3Kβ , PI3Kδ , and PI3Kγ , respectively. (S)-PI3Kα-IN-4 can be used for the research of cancer In Vitro (S)-PI3Kα-IN-4 (compound 11) is a quinazolin-4(3H)-one derivative with 2-substituted-N-methylpropanamide substitution. MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:PI3Kα 2.3 nM (IC 50 )
