compound introduction
BACE1-IN-1 is a potent and highly brain penetrant BACE1 inhibitor with IC 50 s of 32 and 47 nM for human BACE1 and BACE2 , respectively. Form:Solid IC50& Target:IC50: 32 nM (human BACE1), 47 nM (human BACE2)
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BACE1-IN-1
CAS number：1310347-50-2 molecular formula：C18H14F3N5O2
overview
Specs
| Chinese alias | - | ||
| English alias | B67UFT75QS | MS-26467 | N-[3-[(4r)-2-Azanylidene-5,5-Bis(Fluoranyl)-4-Methyl-1,3-Oxazinan-4-Yl]-4-Fluoranyl-Phenyl]-5-Cyano-Pyridine-2-Carboxamide | RG7129 | 2-Pyridinecarboxamide, N-(3-((4R)-2-amino-5,5-difluoro-5,6-dihydro-4-methyl-4H-1,3-oxazin-4-yl)-4 | ||
| CAS number | 1310347-50-2 | molecular formula | C18H14F3N5O2 |
| molecular weight | 389.33 g/mol | Exact mass | ≥99% |
| PSA | 113.000 Ų | logp | 1.700 |
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