Nebicapone (BIA 3-202), a reversible catechol-O-methyltransferase (COMT) inhibitor, is mainly metabolized by glucuronidation. Nebicapone is mainly peripherally acting inhibitor that decreases the biotransformation of L-DOPA to 3-O-methyl-DOPA by inhibition of COMT , and it is potential for the treatment of Parkinson's disease. Form:Solid
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Nebicapone
CAS number:274925-86-9 molecular formula:C14H11NO5
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| Chinese alias | 奈比卡朋 | ||
| English alias | Ethanone, 1-(3,4-dihydroxy-5-nitrophenyl)-2-phenyl- | BIA 3-202 | 1-(3,4-dihydroxy-5-nitro-phenyl)-2-phenyl-ethanone | Q21547145 | SCHEMBL132167 | NM2KXJ990T | DTXSID30181912 | 1-(3,4-dihydroxy-5-nitrophenyl)-2-phenylethanone | BDBM50108878 | 3-NITRO-5-PH | ||
| CAS number | 274925-86-9 | molecular formula | C14H11NO5 |
| molecular weight | 273.24 g/mol | Exact mass | ≥99% |
| PSA | 103.000 Ų | logp | 2.9 |
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