FABP-IN-1 (Compounds 4b) is a high affinity fatty acid binding protein (FABP) inhibitor. FABP-IN-1 inhibits FABP3 , FABP5 , and FABP7 with K i values of 0.69 μM, 0.55 μM and 0.67 μM, respectively. FABP-IN-1 displays potent antinociceptive effects In Vivo FABP-IN-1 (Compounds 4b; 20 mg/kg; intraperitoneal injection; for 90 minutes; male wild-type C57BL/6 mice) treatment displays potent antinociceptive effects in CFA model . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Male wild-type C57BL/6 mice injected with complete Freund’s adjuvant (CFA) Dosage: 20 mg/kg Administration: Intraperitoneal injection; for 90 minutes Result: Displayed potent antinociceptive effects in CFA model. Form:Solid IC50& Target:Ki: 0.69 μM (FABP3), 0.55 μM (FABP5) and 0.67 μM (FABP7)
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FABP-IN-1
CAS number：2132990-90-8 molecular formula：C30H26O6
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 2132990-90-8 | molecular formula | C30H26O6 |
| molecular weight | 482.52 g/mol | Exact mass | ≥98% |
| PSA | - | logp | - |
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