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AGN 196996

CAS number:958295-17-5    molecular formula:C24H20BrNO5

overview

compound introduction

AGN 196996 is a potent and selective RARα antagonist with Ki value of 2 nM; little binding affinity for RARβ(Ki=1087 nM) and RARγ(Ki=8523 nM).IC50 value: 2 nM(Ki)Target: RARα antagonistAGN 196996 shows no activity in transactivation assays, but instead block the gene transcriptional activity induced by ATRA and other RAR agonists. Form:Solid

Specs

Chinese alias编号 196996
English alias-
CAS number958295-17-5molecular formulaC24H20BrNO5
molecular weight482.32 g/molExact mass≥99%
PSA92.700 Ųlogp5.000

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