AGN 196996 is a potent and selective RARα antagonist with Ki value of 2 nM; little binding affinity for RARβ(Ki=1087 nM) and RARγ(Ki=8523 nM).IC50 value: 2 nM(Ki)Target: RARα antagonistAGN 196996 shows no activity in transactivation assays, but instead block the gene transcriptional activity induced by ATRA and other RAR agonists. Form:Solid
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AGN 196996
CAS number:958295-17-5 molecular formula:C24H20BrNO5
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| Chinese alias | 编号 196996 | ||
| English alias | - | ||
| CAS number | 958295-17-5 | molecular formula | C24H20BrNO5 |
| molecular weight | 482.32 g/mol | Exact mass | ≥99% |
| PSA | 92.700 Ų | logp | 5.000 |
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