Reserpine hydrochloride

Reserpine hydrochloride is an inhibitor of the vesicular monoamine transporter 2 ( VMAT2 ). In Vitro Reserpine hydrochloride is an inhibitor of the vesicular monoamine transporter 2 (VMAT2). Reserpine hydrochloride displays a significant on the density of dopamine D1 receptors (F 2,12 =8.81, p In Vivo Withdrawal (48 h) from chronic (14-day) but not acute Reserpine hydrochloride administration in a dose of 0.2 mg/kg i.p. produces a significant reduction of the immobility time (F 2,18 =3.68, p Cell Assay JB6 P+ cells are seeded in 96-well plates containing Minimum essential media (MEM) at a density of 1×10 4 cells/mL ( 100 μL/well ) for 1, 3, and 5 days, and HepG2-C8 cells are seeded in plates containing DMEM. After incubation for 24 h, the cells are treated with either DMSO or various concentrations of Reserpine hydrochloride . For JB6 P+ cells, the medium is changed every 2 days for the 3-day and 5-day treatments. Cell viability is assessed using a MTS assay kit according to the manufacturer’s instructions. The absorbance of the formazan product is read at 490 nm, and the cell viability is calculated and compared with the DMSO control group. MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:VMAT2

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