TrkA-IN-3 is a potent, subselective and allosteric TrkA inhibitor, with an IC 50 of 22.4 nM. TrkA-IN-3 shows more than 8000-fold selectivity for TrkA over TrkB and TrkC . TrkA-IN-3 can be used for the research of pain. Appearance:Solid IC50& Target:TrkA 22.4 nM (IC 50 ) In Vitro:TrkA-IN-3 (compound 5) demonstrates 73.9% and 64.8% of kinase inhibition towards TrkA at concentrations of 1 μM and 0.1 μM , respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Biological Activity:TrkA-IN-3 is a potent, subselective and allosteric TrkA inhibitor, with an IC 50 of 22.4 nM. TrkA-IN-3 shows more than 8000-fold selectivity for TrkA over TrkB and TrkC . TrkA-IN-3 can be used for the research of pain.
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TrkA-IN-3
CAS number：unknown molecular formula：C24H17F3N4O3
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | C24H17F3N4O3 |
| molecular weight | 466.41 g/mol | Exact mass | ≥98% |
| PSA | - | logp | - |
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