ZINC00640089 is a specific Lipocalin-2 ( LCN2 ) inhibitor. ZINC00640089 inhibits cell proliferation, cell viability and reduces AKT phosphorylation levels in SUM149 cells. ZINC00640089 has good potential for research in inflammatory breast cancer (IBC) In Vitro ZINC00640089 (0.01-100 µM; 72 h) reduces cell proliferation and cell viability in SUM149 cells. ZINC00640089 (1, 10 µM; 15 min, 1 h) reduces the p-Akt levels in SUM149 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: SUM149 cells Concentration: 0.01-100 µM Incubation Time: 72 h Result: Reduced cell viability at concentrations of 1 µM or lower. Western Blot AnalysisCell Line: SUM149 cells Concentration: 1, 10 µM Incubation Time: 15 min, 1 h, 24 h Result: Reduced the p-Akt protein levels 15 min and 1 h and changes in the p-Akt protein levels were not observed at 24 h. Form:Solid IC50& Target:LCN2
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ZINC00640089
CAS number：667880-11-7 molecular formula：C20H13F3N2O2
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 667880-11-7 | molecular formula | C20H13F3N2O2 |
| molecular weight | 370.32 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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