compound introduction
SSTR5 antagonist 2 hydrochloride is a highly potent, oral active and selective somatostatin (receptor) subtype 5 (SSTR5) antagonist and has potential for the research of type 2 diabetes mellitus (T2DM). Appearance:Solid In Vivo:SSTR5 antagonist 2 (compound 10) (10mg/kg, orally) hydrochloride increases both total and active circulating incretin hormone GLP1 levels in mice at a dose of 10mg/kg. SSTR5 antagonist 2 hydrochloride increases pancreatic insulin secretion as well Biological Activity:SSTR5 antagonist 2 hydrochloride is a highly potent, oral active and selective somatostatin (receptor) subtype 5 (SSTR5) antagonist and has potential for the research of type 2 diabetes mellitus (T2DM).
