Orexin B, rat, mouse (Rat orexin B) TFA is an endogenous orexin receptor agonist. Orexin B, rat, mouse TFA binds and activates two closely related orphan G protein-coupled receptors OX1-R and OX2-R. Orexin B, rat, mouse TFA stimulates food intake and ener Appearance:Solid In Vitro:OX2 receptor is indeed a high-affinity receptor for human orexin B, with an IC 50 of 36 nM in the binding assay and an EC 50 of 60 nM in the [Ca 2+ ]i transient assay. Human Orexin B has significantly lower affinity for the human OX1: the calculated IC 50 In Vivo:Orexin-B modulates the activity of rod bipolar cells (RBCs) located in the outer retina of rat. Intravitreal injection of orexin-B increased the amplitude of the scotopic electroretinographic b-wave, a reflection of RBC activity, recorded in vivo. MC Biological Activity:Orexin B, rat, mouse (Rat orexin B) TFA is an endogenous orexin receptor agonist. Orexin B, rat, mouse TFA binds and activates two closely related orphan G protein-coupled receptors OX1-R and OX2-R. Orexin B, rat, mouse TFA stimulates food intake and ener
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Orexin B, rat, mouse TFA
CAS number：unknown molecular formula：C₁₂₈H₂₁₆F₃N₄₅O₃₆S
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| Chinese alias | Orexin B，大鼠，小鼠 TFA | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | C₁₂₈H₂₁₆F₃N₄₅O₃₆S |
| molecular weight | 3050.42 g/mol | Exact mass | ≥98% |
| PSA | - | logp | - |
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