CTOP TFA is a potent and highly selective μ-opioid receptor antagonist. CTOP TFA antagonizes the acute analgesic effect and hypermotility. CTOP TFA enhances extracellular dopamine levels in the nucleus accumbens. CTOP TFA dose-dependently enhances locomot Appearance:Solid IC50& Target:μ Opioid Receptor/MOR In Vivo:CTOP TFA (0-0.5 nmol, ICV, once) antagonizes the analgesic effect in a dose-dependent manner. CTOP TFA (0-2 nmol, ICV, once) causes withdrawal hypothermia and a loss of body weight in animals. CTOP TFA (0-1.5 nmol per side, Intra-VTA injection) Biological Activity:CTOP TFA is a potent and highly selective μ-opioid receptor antagonist. CTOP TFA antagonizes the acute analgesic effect and hypermotility. CTOP TFA enhances extracellular dopamine levels in the nucleus accumbens. CTOP TFA dose-dependently enhances locomot
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CTOP TFA
CAS number：unknown molecular formula：C52H68F3N11O13S2
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| Chinese alias | 氯丙烷三氟乙酸 | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | C52H68F3N11O13S2 |
| molecular weight | 1176.28 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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