Aldometanib (LXY-05-029) is an orally active aldolase inhibitor. Aldometanib can activate lysosomal adenosine monophosphate-activated protein kinase (AMPK) and decreases blood glucose. Aldometanib can be used for the research of metabolic homeostasis Appearance:Solid In Vitro:Aldometanib (0-1000 nM; 2 h) activates AMPK by preventing aldolase from binding to FBP to engender a pseudo-starvation signal. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Western Blot AnalysisC In Vivo:Aldometanib (oral; 0-10 mpk) reduces blood glucose in lean mice. Aldometanib (oral; 2-10 mpk; twice daily; for a week) reduces blood glucose and alleviates fatty liver in obese hyperglycaemic mice. Aldometanib alleviates fatty liver and nonalcoh Biological Activity:Aldometanib (LXY-05-029) is an orally active aldolase inhibitor. Aldometanib can activate lysosomal adenosine monophosphate-activated protein kinase (AMPK) and decreases blood glucose. Aldometanib can be used for the research of metabolic homeostasis
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Aldometanib
CAS number：unknown molecular formula：C27H43Cl2IN2
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| Chinese alias | 阿多美他尼 | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | C27H43Cl2IN2 |
| molecular weight | 593.45 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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