CAS number：67165-56-4 molecular formula：C17H17Cl2NO
Diclofensine(Ro-8-4650)是高效单胺再摄取抑制剂，大鼠脑突触体中阻断多巴胺、去甲肾上腺素和5-羟色胺的IC50值分别为0.74、2.3和3.7nM。 Diclofensine(Ro-8-4650) is a potent inhibitor of monoamine reuptake, blocking the uptake of dopamine, noradrenaline, and serotonin by rat brain synaptosomes with IC50 values of 0.74, 2.3, and 3.7 nM, respectively.
| Chinese alias | 双氮奋兴 | 4-(3,4-二氯苯)-7-甲氧基-2-甲基-1,2,3,4-四氢异喹啉 | 双氯芬辛 | ||
| English alias | Ro 8-4650 | 4-(3,4-dichlorophenyl)-7-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline | ||
| CAS number | 67165-56-4 | molecular formula | C17H17Cl2NO |
| molecular weight | 322.24 g/mol | Exact mass | ≥97% |
| PSA | 12.500 Ų | logp | 4.500 |
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