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5-Iodo-indirubin-3'-monoxime

CAS number:331467-03-9    molecular formula:C16H10IN3O2

overview

compound introduction

5-Iodo-indirubin-3'-monoxime is a potent GSK-3β , CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase, with IC 50 s of 9, 20 and 25 nM, respectively Form:Solid IC50& Target:GSK-3β 9 nM (IC 50 ) Cdk5/p25 20 nM (IC 50 ) Cdk1/cyclin B 25 nM (IC 50 )

Specs

Chinese alias5-碘靛玉红-3'-一肟
English alias-
CAS number331467-03-9molecular formulaC16H10IN3O2
molecular weight403.17 g/molExact mass≥99%
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