5-Iodo-indirubin-3'-monoxime is a potent GSK-3β , CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase, with IC 50 s of 9, 20 and 25 nM, respectively Form:Solid IC50& Target:GSK-3β 9 nM (IC 50 ) Cdk5/p25 20 nM (IC 50 ) Cdk1/cyclin B 25 nM (IC 50 )
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5-Iodo-indirubin-3'-monoxime
CAS number:331467-03-9 molecular formula:C16H10IN3O2
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| Chinese alias | 5-碘靛玉红-3'-一肟 | ||
| English alias | - | ||
| CAS number | 331467-03-9 | molecular formula | C16H10IN3O2 |
| molecular weight | 403.17 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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