Hydrochlorothiazid- 13 C,d 2 is the 13 C- and deuterium labeled Hydrochlorothiazide. Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect. In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs [71] . MCE has not independently confirmed the accuracy of these methods. They are for reference only.
All
Chemical Reagents
Biomedicine
Organic raw materials
Inorganic chemical industry
intermediate
Agricultural chemicals
Auxiliaries and catalysts
Fragrances and Flavors
Dyes and Pigments
Daily chemical industry
Hydrochlorothiazid-13C,d2
CAS number：1190006-03-1 molecular formula：C613CH6D2ClN3O4S2
overview
compound introduction
Specs
| Chinese alias | 氢氯噻嗪-13C,d2 | ||
| English alias | HY-B0252S1 | Hydrochlorothiazide-13C,d2 | 1190006-03-1 | Hydrochlorothiazid-13C,d2 | 6-Chloro-1,1-dioxo(3-~13~C,3,3-~2~H_2_)-1,2,3,4-tetrahydro-1lambda~6~,2,4-benzothiadiazine-7-sulfonamide | DTXSID00662001 | 6-chloro-3,3-dideuterio-1,1-dioxo-2,4-dihydro- | ||
| CAS number | 1190006-03-1 | molecular formula | C613CH6D2ClN3O4S2 |
| molecular weight | 300.74 g/mol | Exact mass | - |
| PSA | - | logp | - |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
No safety information yet
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 0 shareMSDS
