Ulixertinib hydrochloride (BVD-523 hydrochloride) is a potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases, with an IC 50 of In Vitro Combined Ulixertinib (BVD-523; 10, 20, 30 μM; 48 hours) and VS-5584 treatment causes significant induction of cell death in human pancreatic cancer (HPAC) cells in PDAC cell lines BxPC-3, MIAPaCa-2, and CFPAC-1. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
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Ulixertinib hydrochloride
CAS number:1956366-10-1(DMSO) molecular formula:C21H23Cl3N4O2
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| Chinese alias | 盐酸乌利塞替尼 | ||
| English alias | - | ||
| CAS number | 1956366-10-1(DMSO) | molecular formula | C21H23Cl3N4O2 |
| molecular weight | 469.8 g/mol | Exact mass | 10mM in DMSO |
| PSA | - | logp | - |
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