CAS number：1597440-03-3(DMSO) molecular formula：C20H23N3O
(Rac)-BRD0705 is a less active racemate of BRD0705. BRD0705 is a potent, paralog selective and orally active GSK3α inhibitor with an IC 50 of 66 nM and a K d of 4.8 μM. BRD0705 displays increased selectivity for GSK3α (8-fold) versus GSK3β (IC 50 of 515 nM). BRD0705 can be used for acute myeloid leukemia (AML).
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| CAS number | 1597440-03-3(DMSO) | molecular formula | C20H23N3O |
| molecular weight | 321.42 g/mol | Exact mass | 10mM in DMSO |
| PSA | - | logp | - |
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