CAS number：1584647-27-7 molecular formula：C26H25F7N4O3
Notch inhibitor 1 is a potent Notch inhibitor, with IC 50 s of 7.8 and 8.5 nM for Notch 1 and Notch 3, respectively. Used in the research of cancer In Vitro Notch inhibitor 1 (Example 1) potently inhibits Notch signaling pathway. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:IC50: 7.8 nM (Notch 1), 8.5 nM (Notch 3)
| Chinese alias | 缺口抑制剂1 | ||
| English alias | Butanediamide, N1-((3S)-5-(3-fluorophenyl)-2,3-dihydro-9-methyl-2-oxo-1H-1,4-benzodiazepin-3-yl)-2,3-bis(3,3,3-trifluoropropyl)-, (2R,3S)- | SCHEMBL15608290 | (2S,3R)-N'-[(3S)-5-(3-fluorophenyl)-9-methyl-2-oxo-1,3-dihydro-1,4-benzodiazepin-3-yl]-2,3-bis(3 | ||
| CAS number | 1584647-27-7 | molecular formula | C26H25F7N4O3 |
| molecular weight | 574.49 g/mol | Exact mass | ≥99% |
| PSA | 114.000 Ų | logp | 4.800 |
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