(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) is a potent and competitive antagonist of parathyroid hormone (PTH) , with a K i of 69 nM in bovine renal cortical membrane. (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) can be used for growth and development regulation In Vitro (D-Trp12,Tyr34)-pTH (7-34) amide (0.05-10 μM) causes a concentration-dependent inhibition of PTHrP or PTH-stimulated cAMP formation in opossum kidney (OK) cells. (D-Trp12,Tyr34)-pTH (7-34) amide (0.1-10 μM) attenuates inhibition of Nap i T promoted by 1 nM of either PTHrP or PTH. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo (D-Trp12,Tyr34)-pTH (7-34) amide (1 mg/mL once, 0.1 mg/mL for 6 h; i.v.) has no significant effect on serum calcium levels in hypercalcemic athymic nude mice bearing a human squamous cell carcinoma of the lung. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:Ki: 69 nM (PTH)
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(D-Trp12,Tyr34)-pTH (7-34) amide (bovine)
CAS number：118102-98-0 molecular formula：C165H251N49O40S2
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| Chinese alias | (D-Trp12,Tyr34)-pTH (7-34) 酰胺(牛) | ||
| English alias | - | ||
| CAS number | 118102-98-0 | molecular formula | C165H251N49O40S2 |
| molecular weight | 3625.25 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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