Ridogrel (R 68070) is an orally active combined thromboxane A2 synthetase inhibitor and thromboxane A2/prostaglandin endoperoxide receptor blocker. Ridogrel is potent antiplatelet agent. Anti-inflammatory activities . In Vitro In rats, R 68 070 (1.25 mg/kg orally, -2 h) singly prolongs tail bleeding times as much as a combination of TXA2 synthetase inhibition (dazoxiben 10 mg/kg) and TXA2/prostaglandin endoperoxide receptor blockade (BM 13177 40 mg/kg). In dogs, the compound reduces coronary thrombosis induced by electrical damage (1.25 mg/kg i.v.) and prevents the evolution of occlusion/reperfusion-induced arrhythmias into ventricular fibrillation (2.5 mg/kg i.v.) [2 . MCE has not independently confirmed the accuracy of these methods. They are for reference only.
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Ridogrel
CAS number：110140-89-1(DMSO) molecular formula：C18H17F3N2O3
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| Chinese alias | 利多格雷 | ||
| English alias | - | ||
| CAS number | 110140-89-1(DMSO) | molecular formula | C18H17F3N2O3 |
| molecular weight | 366.33 g/mol | Exact mass | 10mM in DMSO |
| PSA | - | logp | - |
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