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MPT0E028

CAS number:1338320-94-7    molecular formula:C17H16N2O4S

overview

compound introduction

MPT0E028 is an orally active and selective HDAC inhibitor with IC 50 s of 53.0 nM, 106.2 nM, 29.5 nM for HDAC1 , HDAC2 and HDAC6 , respectively. MPT0E028 reduces the viability of B-cell lymphomas by inducing apoptosis and possesses potent direct Akt targeting ability and reduces Akt phosphorylation in B-cell lymphoma. MPT0E028 has good anticancer activity . Form:Solid

Specs

Chinese alias-
English aliasMPT0E028 | HY-124295 | Q27289720 | 1338320-94-7 | (E)-3-[1-(benzenesulfonyl)-2,3-dihydroindol-5-yl]-N-hydroxyprop-2-enamide | T65L58FI65 | 2-Propenamide, 3-(2,3-dihydro-1-(phenylsulfonyl)-1H-indol-5-yl)-N-hydroxy- | MS-25283 | SCHEMBL2511433 | UNII-T65L58
CAS number1338320-94-7molecular formulaC17H16N2O4S
molecular weight344.38 g/molExact mass≥99%
PSA95.100 Ųlogp1.900

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