MPT0E028 is an orally active and selective HDAC inhibitor with IC 50 s of 53.0 nM, 106.2 nM, 29.5 nM for HDAC1 , HDAC2 and HDAC6 , respectively. MPT0E028 reduces the viability of B-cell lymphomas by inducing apoptosis and possesses potent direct Akt targeting ability and reduces Akt phosphorylation in B-cell lymphoma. MPT0E028 has good anticancer activity . Form:Solid
All
Chemical Reagents
Biomedicine
Organic raw materials
Inorganic chemical industry
intermediate
Agricultural chemicals
Auxiliaries and catalysts
Fragrances and Flavors
Dyes and Pigments
Daily chemical industry
MPT0E028
CAS number:1338320-94-7 molecular formula:C17H16N2O4S
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | MPT0E028 | HY-124295 | Q27289720 | 1338320-94-7 | (E)-3-[1-(benzenesulfonyl)-2,3-dihydroindol-5-yl]-N-hydroxyprop-2-enamide | T65L58FI65 | 2-Propenamide, 3-(2,3-dihydro-1-(phenylsulfonyl)-1H-indol-5-yl)-N-hydroxy- | MS-25283 | SCHEMBL2511433 | UNII-T65L58 | ||
| CAS number | 1338320-94-7 | molecular formula | C17H16N2O4S |
| molecular weight | 344.38 g/mol | Exact mass | ≥99% |
| PSA | 95.100 Ų | logp | 1.900 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
No safety information yet
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 0 shareMSDS





