YZ129 is an inhibitor of the HSP90-calcineurin-NFAT pathway against glioblastoma, directly binding to heat shock protein 90 (HSP90) with an IC 50 of 820 nM on NFAT nuclear translocation. YZ129-induced GBM cell-cycle arrest at the G2/M phase promotes apoptosis and inhibited tumor cell proliferation and migration Form:Solid IC50& Target:HSP90
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YZ129
CAS number:1643120-60-8 molecular formula:C19H12N2O2
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 1643120-60-8 | molecular formula | C19H12N2O2 |
| molecular weight | 300.31 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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