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YZ129

CAS number:1643120-60-8    molecular formula:C19H12N2O2

overview

compound introduction

YZ129 is an inhibitor of the HSP90-calcineurin-NFAT pathway against glioblastoma, directly binding to heat shock protein 90 (HSP90) with an IC 50 of 820 nM on NFAT nuclear translocation. YZ129-induced GBM cell-cycle arrest at the G2/M phase promotes apoptosis and inhibited tumor cell proliferation and migration Form:Solid IC50& Target:HSP90

Specs

Chinese alias-
English alias-
CAS number1643120-60-8molecular formulaC19H12N2O2
molecular weight300.31 g/molExact mass≥99%
PSA-logp-

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