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LASV inhibitor 3.3

CAS number:554438-52-7    molecular formula:C30H37N3O2

overview

compound introduction

LASV inhibitor 3.3 is a Lassa fever virus ( LASV ) inhibitor. LASV inhibitor 3.3 binds with LASV glycoprotein (GP) and promotes virus membrane fusion and infection. LASV inhibitor 3.3 can be used for LASV infection research. In Vitro LASV inhibitor 3.3 (1 nM-100 μM; 1 h) inhibits transduction by murine leukemia virus (MLV) pseudotyped with the indicated viral glycoproteins with an IC 50 value of 1.8 μM. LASV inhibitor 3.3 (1 and 10 μM; 1 h) inhibits LAMP1 binding to LASV GP in vitro. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Western Blot AnalysisCell Line: 293T LAMP1 KO cells expressing LASV GP-His and 293T pX459 cells Concentration: 1 and 10 μM Incubation Time: 1 hour Result: Inhibited the LASV GP binds to LAMP1. Form:Solid

Specs

Chinese aliasLASV 抑制剂 3.3
English alias-
CAS number554438-52-7molecular formulaC30H37N3O2
molecular weight471.63 g/molExact mass≥99%
PSA52.700 Ųlogp4.700

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