LASV inhibitor 3.3 is a Lassa fever virus ( LASV ) inhibitor. LASV inhibitor 3.3 binds with LASV glycoprotein (GP) and promotes virus membrane fusion and infection. LASV inhibitor 3.3 can be used for LASV infection research. In Vitro LASV inhibitor 3.3 (1 nM-100 μM; 1 h) inhibits transduction by murine leukemia virus (MLV) pseudotyped with the indicated viral glycoproteins with an IC 50 value of 1.8 μM. LASV inhibitor 3.3 (1 and 10 μM; 1 h) inhibits LAMP1 binding to LASV GP in vitro. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Western Blot AnalysisCell Line: 293T LAMP1 KO cells expressing LASV GP-His and 293T pX459 cells Concentration: 1 and 10 μM Incubation Time: 1 hour Result: Inhibited the LASV GP binds to LAMP1. Form:Solid
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LASV inhibitor 3.3
CAS number:554438-52-7 molecular formula:C30H37N3O2
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| Chinese alias | LASV 抑制剂 3.3 | ||
| English alias | - | ||
| CAS number | 554438-52-7 | molecular formula | C30H37N3O2 |
| molecular weight | 471.63 g/mol | Exact mass | ≥99% |
| PSA | 52.700 Ų | logp | 4.700 |
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