Omaciclovir (H2G) is a potent and selective inhibitor of herpesvirus replication. Omaciclovir is a nucleoside analog with antiviral activity. In Vitro Omaciclovir is a nucleoside analog with in vitro inhibitory activity against varicella-zoster virus (VZV), herpes simplex virus types 1 and 2 (HSV-1 and -2), Epstein-Barr virus, and human herpesvirus 6. Omaciclovir is also efficacious in simian varicella virus-infected monkeys. Omaciclovir shows antiviral activities against different human herpesviruses with EC 50 s of 0.72 ± 0.1, 0.62 ± 0.2, 0.015 ± 0.004, 0.048 ± 0.023, 0.047 ± 0.004, 0.035 ± 0.022, and 0.016 ± 0.003 μM for MRC-5 VZV-32, MRC-5 Molly, MeWo VZV-32, MeWo Molly, MeWo Emily, MeWo VZ11, and MeWo VZ30, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
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Omaciclovir
CAS number:124265-89-0(DMSO) molecular formula:C10H15N5O3
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| Chinese alias | 奥马昔洛韦 | ||
| English alias | - | ||
| CAS number | 124265-89-0(DMSO) | molecular formula | C10H15N5O3 |
| molecular weight | 253.26 g/mol | Exact mass | 10mM in DMSO |
| PSA | - | logp | - |
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