compound introduction
INO-1001 is a potent and selective poly (ADP-ribose) polymerase (PARP) inhibitor. INO-1001 is a potent enhancer of radiation sensitivity and enhances radiation-induced cell killing by interfering with DNA repair mechanisms, resulting in necrotic cell death INO-1001 has anti-tumor effects . In Vitro INO-1001 has an IC 50 of 0.05 μM in Chinese hamster ovary AA8 (CHO) cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:PARP
