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K-Ras G12C-IN-3

CAS number:1629268-19-4(DMSO)    molecular formula:C21H19Cl3N2O3

overview

compound introduction

K-Ras G12C-IN-3 is a novel and irreversible inhibitor of mutant K-ras G12C.IC50 value:Target: K-ras G12C inhibitorFor more information, please see the following patent.Heterocyclic compounds as covalent inhibitors of G12C mutant K-Ras protein useful for treating cancers, and preparation thereofBy Ren, Pingda; Liu, Yi; Li, Liansheng; Feng, Jun; Wu, TaoFrom PCT Int. Appl. (2014), WO 2014152588 A1 20140925.

Specs

Chinese alias-
English alias-
CAS number1629268-19-4(DMSO)molecular formulaC21H19Cl3N2O3
molecular weight453.75 g/molExact mass10mM in DMSO
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