(2-pyridyldithio)-PEG4-propargyl is a PEG derivative which contains a pyridyl disulfide moiety and a propargyl group. The pyridyl disulfide group can react with thiol groups of proteins over a wide range of pH levels. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The hydrophilic PEG linker increases the water solubility of compounds in aqueous media.
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(2-pyridyldithio)-PEG4-propargyl
CAS number:2170240-99-8 molecular formula:C16H23NO4S2
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| Chinese alias | - | ||
| English alias | HY-141360 | BP-23858 | AKOS040740997 | DTXSID601197561 | MS-25613 | 2-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethyldisulfanyl]pyridine | C70190 | Pyridine, 2-(3,6,9,12-tetraoxapentadec-14-yn-1-yldithio)- | 2170240-99-8 | (2-pyridyldithio)-PEG4-propar | ||
| CAS number | 2170240-99-8 | molecular formula | C16H23NO4S2 |
| molecular weight | 357.5 g/mol | Exact mass | ≥98% |
| PSA | 100.000 Ų | logp | 1.300 |
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