Elubrixin tosylate (SB-656933 tosylate) is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist. Elubrixin tosylate inhibits neutrophil CD11b upregulation ( IC 50 of 260.7 nM) and shape change ( IC 50 of 310.5 nM). Elubrixin tosylate has the potential for inflammatory diseases research, such as inflammatory bowel disease and airway inflammation In Vitro Elubrixin has an inhibitory effect on neutrophils in a dose-dependent fashion. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:CXCR2|IL-8
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Elubrixin tosylate
CAS number:960495-43-6 molecular formula:C24H25Cl2FN4O7S2
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| Chinese alias | 伊布瑞欣甲磺酸盐 | ||
| English alias | D10420 | DTXSID60242106 | Elubrixin tosylate (USAN) | MS-30886 | SB-656933-AAA | 13FVR7WD4P | ELUBRIXIN TOSILATE [WHO-DD] | AKOS040758495 | Elubrixin (tosylate) | Elubrixin tosylate | Urea, N-(2-chloro-3-fluorophenyl)-N'-(4-chloro-2-hydroxy-3-(1- piperazi | ||
| CAS number | 960495-43-6 | molecular formula | C24H25Cl2FN4O7S2 |
| molecular weight | 635.51 g/mol | Exact mass | ≥99% |
| PSA | 182.000 Ų | logp | - |
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