compound introduction
NRX-252262 is a potent enhancer of the interaction between β-Catenin , and its cognate E3 ligase , SCF β-TrCP , induces mutant β-catenin degradation, with an EC 50 of 3.8 nM In Vitro NRX-252262 (35 μM) causes S33E/S37A mutant β-catenin degradation in cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:EC50: 3.8 nM (β-Catenin-SCF β-TrCP )
